2014年 発表論文


  • Production of 16.5% v/v ethanol from seagrass seeds.
    Uchida M, Miyoshi T, Kaneniwa M, Ishihara K, Nakashimada Y, Urano N.
    J Biosci Bioeng., 2014 Dec., 118(6):646-50. [PubMed]
  • Dietary restriction involves NAD(+) -dependent mechanisms and a shift toward oxidative metabolism.
    Moroz N, Carmona JJ, Anderson E, Hart AC, Sinclair DA, Blackwell TK.
    Aging Cell., 2014 Dec., 13(6):1075-85. [PubMed]
  • The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program.
    Itoh-Nakadai A, Hikota R, Muto A, Kometani K, Watanabe-Matsui M, Sato Y, Kobayashi M, Nakamura A, Miura Y, Yano Y, Tashiro S, Sun J, Ikawa T, Ochiai K, Kurosaki T, Igarashi K.
    Nat Immunol., 2014 Dec., 15(12):1171-80. [PubMed]
  • Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.
    Ewald CY, Landis JN, Abate JP, Murphy CT, Blackwell TK.
    Nature, 2014 Dec 15., doi: 10.1038/nature14021. [PubMed]
  • The microbiota is important for IL-17A expression and neutrophil infiltration in lesional skin of Flgft/ft mice.
    Hoff S, Oyoshi MK, Macpherson A, Geha RS.
    Clin Immunol., 2014 Dec 12., S1521-6616(14)00268-X. [PubMed]
  • The tap-tpg gene pair on the linear plasmid functions to maintain a linear topology of the chromosome in Streptomyces rochei.
    Nindita Y, Cao Z, Yang Y, Arakawa K, Shiwa Y, Yoshikawa H, Tagami M, Lezhava A, Kinashi H.
    Mol Microbiol., 2014 Dec 11., doi: 10.1111/mmi.12904. [PubMed]
  • A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40/MEK-ERK pathway.
    Miyamoto J, Mizukure T, Park SB, Kishino S, Kimura I, Hirano K, Bergamo P, Rossi M, Suzuki T, Arita M, Ogawa J, Tanabe S.
    J Biol Chem., 2014 Dec 10., jbc.M114.610733. [PubMed]
  • Identification of Pseudomonas fluorescens Chemotaxis Sensory Proteins for Malate, Succinate, and Fumarate, and Their Involvement in Root Colonization.
    Oku S, Komatsu A, Nakashimada Y, Tajima T, Kato J.
    Microbes Environ., 2014 Dec 10. [PubMed]
  • Blockage of the early step of lankacidin biosynthesis caused a large production of pentamycin, citreodiol and epi-citreodiol in Streptomyces rochei.
    Cao Z, Yoshida R, Kinashi H, Arakawa K.
    J Antibiot., 2014 Dec 3., doi: 10.1038/ja.2014.160. [PubMed]
  • Binding of WIP to actin is essential for T cell actin cytoskeleton integrity and tissue homing.
    Massaad MJ, Oyoshi MK, Kane J, Koduru S, Alcaide P, Nakamura F, Ramesh N, Luscinskas FW, Hartwig J, Geha RS.
    Mol Cell Biol., 2014 Dec 1, 34(23):4343-54. [PubMed]
  • Value-added lipid production from brown seaweed biomass by two-stage fermentation using acetic acid bacterium and thraustochytrid.
    Arafiles KH, Iwasaka H, Eramoto Y, Okamura Y, Tajima T, Matsumura Y, Nakashimada Y, Aki T.
    Appl Microbiol Biotechnol., 2014 Nov, 98(22):9207-16. [PubMed]
  • Clinical outcomes and causes of death in Japanese patients with long-term inferior vena cava filter implants and deep vein thrombosis.
    Iwamoto Y, Okamoto M, Hashimoto M, Fukuda Y, Uchimura Y, Iwamoto A, Matsumoto T, Iwasaki T, Kinoshita H, Ueda H, Kihara Y.
    J Cardiol., 2014 Oct, 64(4):308-11. [PubMed]
  • 3,6-Epidioxy-1,10-bisaboladiene inhibits G1 -specific transcription through Swi4/Swi6 and Mbp1/Swi6 via the Hog1 stress pathway in yeast.
    Imamura Y, Yukawa M, Ueno M, Kimura K, Tsuchiya E.
    FEBS J., 2014 Oct, 281(20):4612-21. [PubMed]
  • Evaluation of marine sediments as microbial sources for methane production from brown algae under high salinity.
    Miura T, Kita A, Okamura Y, Aki T, Matsumura Y, Tajima T, Kato J, Nakashimada Y.
    Bioresour Technol., 2014 Oct, 169:362-6. [PubMed]
  • mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity.
    Mizunuma, M, Neumann-Haefelin, E, Moroz, N, Li, Y, and Blackwell TK.
    Aging Cell, 2014 Oct, 13:869-878.  [PubMed]
  • Prolonged survival by combined treatment with granulocyte colony-stimulating factor and dipeptidyl peptidase IV inhibitor in a rat small-for-size liver transplantation model.
    Hsu LW, Nakano T, Huang KT, Chen CC, Chen KD, Lai CY, Yang SM, Lin CC, Wang CC, Cheng YF, Chiu KW, Kuo YR, Goto S, Chen CL.
    Hepatol Res., 2014 Sep 2, doi: 10.1111/hepr.12413. [PubMed]
  • Insights into the diversity of φRSM phages infecting strains of the phytopathogen Ralstonia solanacearum complex: regulation and evolution.
    Askora A, Kawasaki T, Fujie M, Yamada T.
    Mol Genet Genomics., 2014 Aug, 289(4):589-98. [PubMed]
  • Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast.
    Tang NH, Okada N, Fong CS, Arai K, Sato M, and Toda T.
    FEBS Lett., 2014 Aug 25, 588:2814-2821.  [PubMed]
  • Smoking cessation reverses DNA double-strand breaks in human mononuclear cells.
    Ishida M, Ishida T, Tashiro S, Uchida H, Sakai C, Hironobe N, Miura K, Hashimoto Y, Arihiro K, Chayama K, Kihara Y, Yoshizumi M.
    PLoS One., 2014 Aug 5, 9(8):e103993. [PubMed]
  • Application of a phosphite dehydrogenase gene as a novel dominant selection marker for yeasts.
    Kanda K, Ishida T, Hirota R, Ono S, Motomura K, Ikeda T, Kitamura K, Kuroda A.
    J Biotechnol., 2014 Jul 20, 182-183:68-73. [PubMed]
  • Reorganization of damaged chromatin by the exchange of histone variant H2A.Z-2.
    Nishibuchi I, Suzuki H, Kinomura A, Sun J, Liu NA, Horikoshi Y, Shima H, Kusakabe M, Harata M, Fukagawa T, Ikura T, Ishida T, Nagata Y, Tashiro S.
    Int J Radiat Oncol Biol Phys., 2014 Jul 15, 89(4):736-44. [PubMed]
  • The filamentous phage XacF1 causes loss of virulence in Xanthomonas axonopodis pv. citri, the causative agent of citrus canker disease.
    Ahmad AA, Askora A, Kawasaki T, Fujie M, Yamada T.
    Front Microbiol., 2014 Jul 1, 5:321. [PubMed]
  • CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly.
    Okada N, Toda T, Yamamoto M, and Sato M.
    Mol Biol Cell., 2014 Jul 1, 25: 1969-1982.  [PubMed]
  • Affinity purification of recombinant proteins using a novel silica-binding peptide as a fusion tag.
    Abdelhamid MA, Motomura K, Ikeda T, Ishida T, Hirota R, Kuroda A.
    Appl Microbiol Biotechnol., 2014 Jun, 98(12):5677-84. [PubMed]
  • Late-maturing cooking rice Sensyuraku has excellent properties, equivalent to sake rice, for high-quality sake brewing.
    Anzawa Y, Satoh K, Satoh Y, Ohno S, Watanabe T, Katsumata K, Kume K, Watanabe K, Mizunuma M, Hirata D.
    Biosci Biotechnol Biochem., 2014 Jun 26, 78(11):1954-62.   [PubMed]
  • Anti-inflammatory and Intestinal Barrier-protective Activities of Commensal Lactobacilli and Bifidobacteria in Thoroughbreds: Role of Probiotics in Diarrhea Prevention in Neonatal Thoroughbreds.
    Tanabe S, Suzuki T, Wasano Y, Nakajima F, Kawasaki H, Tsuda T, Nagamine N, Tsurumachi T, Sugaya K, Akita H, Takagi M, Takagi K, Inoue Y, Asai Y, Morita H.
    J Equine Sci., 2014 Jun 25, 25(2):37-43. [PubMed]
  • Regulation of heme oxygenase 1 expression by miR-27b with stem cell therapy for liver regeneration in rats.
    Chen KD, Hsu LW, Goto S, Huang KT, Nakano T, Weng WT, Lai CY, Kuo YR, Chiu KW, Wang CC, Cheng YF, Lin CC, Ma YY, Chen CL.
    Transplant Proc., 2014 May, 46(4):1198-200. [PubMed]
  • Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma.
    Chen KD, Wang CC, Tsai MC, Wu CH, Yang HJ, Chen LY, Nakano T, Goto S, Huang KT, Hu TH, Chen CL, Lin CC.
    Cell Death Dis., 2014 May 22, 5:e1244. [PubMed]
  • The ClpS-like N-domain is essential for the functioning of Ubr11, an N-recognin in Schizosaccharomyces pombe.
    Kitamura K.
    SplingerPlus, 2014 May 20, 3:257 [PubMed]
  • Genetic and metabolomic dissection of the ergothioneine and selenoneine biosynthetic pathway in the fission yeast, S. pombe, and construction of an overproduction system.
    Pluskal T, Ueno M, Yanagida M.
    PLoS One., 2014 May 14, 9(5):e97774. [PubMed]
  • Nap1 stimulates homologous recombination by RAD51 and RAD54 in higher-ordered chromatin containing histone H1.
    Machida S, Takaku M, Ikura M, Sun J, Suzuki H, Kobayashi W, Kinomura A, Osakabe A, Tachiwana H, Horikoshi Y, Fukuto A, Matsuda R, Ura K, Tashiro S, Ikura T, Kurumizaka H.
    Sci Rep., 2014 May 6, 4:4863. [PubMed]
  • Elevation of C-reactive protein level and its correlation with psychiatric comorbidities in recipients after liver transplantation.
    Chen CC, Hsu LW, Nakano T, Goto S, Chen CL.
    Transplant Proc., 2014 Apr, 46(3):894-6. [PubMed]
  • A new subfamily of polyphosphate kinase 2 (class III PPK2) catalyzes both nucleoside monophosphate phosphorylation and nucleoside diphosphate phosphorylation.
    Motomura K, Hirota R, Okada M, Ikeda T, Ishida T, Kuroda A.
    Appl Environ Microbiol., 2014 Apr, 80(8):2602-8. [PubMed]
  • Enhancement of (R)-1,3-butanediol production by engineered Escherichia coli using a bioreactor system with strict regulation of overall oxygen transfer coefficient and pH.
    Kataoka N, Vangnai AS, Ueda H, Tajima T, Nakashimada Y, Kato J.
    Biosci Biotechnol Biochem., 2014 Apr 23, 78(4):695-700. [PubMed]
  • SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.
    Miyagawa K, Low RS, Santosa V, Tsuji H, Moser BA, Fujisawa S, Harland JL, Raguimova ON, Go A, Ueno M, Matsuyama A, Yoshida M, Nakamura TM, Tanaka K.
    Proc Natl Acad Sci U S A., 2014 Apr 22, 111(16):5950-5. [PubMed]
  • Genetic and biochemical analysis of the antibiotic biosynthetic gene clusters on the Streptomyces linear plasmid.
    Arakawa K.
    Biosci Biotechnol Biochem., 2014 Apr 16, 78(2):183-9. [PubMed]
  • Administered chrysanthemum flower oil attenuates hyperuricemia: mechanism of action as revealed by DNA microarray analysis.
    Honda S, Kawamoto S, Tanaka H, Kishida H, Kitagawa M, Nakai Y, Abe K, Hirata D.
    Biosci Biotechnol Biochem., 2014 Apr 16, 78(4):655-61. [PubMed]
  • Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice.
    Takaoka Y, Goto S, Nakano T, Tseng HP, Yang SM, Kawamoto S, Ono K, Chen CL.
    Sci Rep., 2014 Apr 6, 4:5204. [PubMed]
  • Rad51-dependent aberrant chromosome structures at telomeres and ribosomal DNA activate the spindle assembly checkpoint.
    Nakano A, Masuda K, Hiromoto T, Takahashi K, Matsumoto Y, Habib AG, Darwich AG, Yukawa M, Tsuchiya E, and Ueno M.
    Mol Cell Biol., 2014 Apr, 34:1389-1397.  [PubMed]
  • Assessment of reasons for referral and activities of hospital palliative care teams using a standard format: a multicenter 1000 case description.
    Sasahara T, Watakabe A, Aruga E, Fujimoto K, Higashi K, Hisahara K, Hori N, Ikenaga M, Izawa T, Kanai Y, Kinoshita H, Kobayakawa M, Kobayashi K, Kohara H, Namba M, Nozaki-Taguchi N, Osaka I, Saito M, Sekine R, Shinjo T, Suga A, Tokuno Y, Yamamoto R, Yomiya K, Morita T.
    J Pain Symptom Manage., 2014 Mar, 47(3):579-587.e6. [PubMed]
  • Degradation of chloroanilines by toluene dioxygenase from Pseudomonas putida T57.
    Nitisakulkan T, Oku S, Kudo D, Nakashimada Y, Tajima T, Vangnai AS, Kato J.
    J Biosci Bioeng., 2014 Mar, 117(3):292-7. [PubMed]
  • GLTSCR2/PICT1 links mitochondrial stress and Myc signaling.
    Yoon JC, Ling AJ, Isik M, Lee DY, Steinbaugh MJ, Sack LM, Boduch AN, Blackwell TK, Sinclair DA, Elledge SJ.
    Proc Natl Acad Sci U S A., 2014 Mar 11, 111(10):3781-6. [PubMed]
  • IL-10 suppresses IL-17-mediated dermal inflammation and reduces the systemic burden of Vaccinia virus in a mouse model of eczema vaccinatum.
    Darling AR, Freyschmidt EJ, Burton OT, Koleoglou KJ, Oyoshi MK, Oettgen HC.
    Clin Immunol., 2014 Feb, 150(2):153-60. [PubMed]
  • Regulation of polyunsaturated fatty acid biosynthesis by seaweed fucoxanthin and its metabolite in cultured hepatocytes.
    Aki T, Yamamoto M, Takahashi T, Tomita K, Toyoura R, Iwashita K, Kawamoto S, Hosokawa M, Miyashita K, Ono K.
    Lipids., 2014 Feb, 49(2):133-41. [PubMed]
  • The oxidative stress responsive transcription factor Pap1 confers DNA damage resistance on checkpoint-deficient fission yeast cells.
    Belfield C, Queenan C, Rao H, Kitamura K, Walworth NC.
    PLoS One., 2014 Feb 25, 9(2):e89936. [PubMed]
  • Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation.
    Hori A, Ikebe C, Tada M, and Toda T.
    EMBO Rep., 2014 Feb, 15:175-184.  [PubMed]
  • Characterization of bacteriophages Cp1 and Cp2, the strain-typing agents for Xanthomonas axonopodis pv. citri.
    Ahmad AA, Ogawa M, Kawasaki T, Fujie M, Yamada T.
    Appl Environ Microbiol., 2014 Jan, 80(1):77-85. [PubMed]
  • Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast.
    Kajiwara K, Ikeda A, Aguilera-Romero A, Castillon GA, Kagiwada S, Hanada K, Riezman H, Muniz M, and Funato K.
    J Cell Sci., 2014 Jan 15, 15:376-387.  [PubMed]
  • Blockage of the early step of lankacidin biosynthesis caused a large production of pentamycin, citreodiol, and epi-citreodiol in Streptomyces rochei.  Zhisheng Cao, Ryuhei Yoshida, Haruyasu Kinashi, Kenji Arakawa. J. Antibiot., 68 [5], 328-333 (2015). DOI: 10.1038/ja.2014.160


  • Food allergy: Insights into etiology, prevention, and treatment provided by murine models.
    Oyoshi MK, Oettgen HC, Chatila TA, Geha RS, Bryce PJ.
    J Allergy Clin Immunol., 2014 Feb, 133(2):309-17. [PubMed]
  • Role of DNA Damage in Cardiovascular Disease.
    Ishida T, Ishida M, Tashiro S, Yoshizumi M, Kihara Y.
    Circulation Journal, 2014 Jan, Vol. 78 (2014) No. 1 42-50. [Abstract]