Yearly Archives: 2018

(20th April)Takashi Toda attended the 21st board meeting of Japan Microbiology Association held at the Science Council of Japan in Tokyo.

20th April

Takashi Toda attended the 21st board meeting of Japan Microbiology Association held at the Science Council of Japan in Tokyo. The reason for this attendance was to establish and strength the domestic research network between the HiHA and microbiologists/medical researchers to promote collaborative programmes.

(25th May) 29th HiHA Seminar

29th HiHA seminar was held on 25th May (Fri).

【Speaker】
Shinji Fukuda

【Affiliations】

Institute of Advanced Biosciences,Keio University

【Title】

『Shedding light on the function of gut microbiota, another organ in our body』

【Venue】
Building of Graduate School of Advanced Sciences of Matter, 3F ROOM 302S

【Time】
16:00-17:00

【Host】
Masaki Mizunuma

* This lecture is set up as a joint seminar across five graduate schools.

A new paper was published from Takashi Toda and Masashi Yukawa group.

A new paper was published from Takashi Toda and Masashi Yukawa group. This work was achieved through international collaborations performed by three research teams in Hiroshima University (Toda and Yukawa), Iwate University (Ken-ichi Kimura) and CSIR-Central Drug Research Institute in India (Shakil Ahmed). The research was in part supported by a JSPS grant “Fostering international researchers through the collaborative research network focusing on the mechanisms of lifespan regulation ”.

This study is partly supported by Program for Advancing Strategic International Networks to Accelerate the Circulation of Talented Researchers (S2902), in which Takashi Toda is a principal investigator and Shakil Ahmed is a calloborative researcher.

Authors: Masashi Yukawa, Tomoaki Yamauchi, Naoaki Kurisawa, Shakil Ahmed, Ken-ichi Kimura, and Takashi Toda

Titile: Fission yeast cells overproducing HSET/KIFC1 provides a useful tool for identification and evaluation of human kinesin-14 inhibitors

Journal: Fungal Genetics and Biology, in press　Volume 116, July 2018, Pages 33–41
Doi: https://doi.org/10.1016/j.fgb.2018.04.006

A new paper on which Dr. Seiji Kawamoto and Dr. Takashi Fujimura are co-authors was published in the Cytotechnology.

Dr Kazunori Kume returned from the Francis Crick Institute (Sir Paul Nurse group) after 3-month stay. Welcome back.

『Announcement』

Dr Kazunori Kume returned from the Francis Crick Institute (Sir Paul Nurse group) after 3-month stay. Welcome back.

9th and 10th March A HIHA member, Dr Kenji Arakawa visited the Harvard University, Harvard Medical School and Boston Children’s Hospital, and discussed progress of our international research collaboration with Dr Michiko Oyoshi.

9th and 10th March

Kenji Arakawa

A HIHA member, Dr Kenji Arakawa visited the Harvard University, Harvard Medical School and Boston Children’s Hospital, and discussed progress of our international research collaboration with Dr Michiko Oyoshi. Dr Arakawa also met and discussed progress with Dr. Takashi Fujimura, who is a visiting scientist in Dr Oyoshi’s group from Hiroshima University supported by HIHA and JSPS-funded "Program for Advancing Strategic International Networks to Accelerate the Circulation of Talented Researchers”.

Takashi Fujimura

(12th March)5th HiHA International Symposium

5th HiHA International Symposium was be held on 12th March (Mon).

【Venue】
Building of Graduate School of Advanced Sciences of Matter, 4F ROOM 401N

【Time】
13:00-17:30

【Prograｍ】

Opening Remarks Takashi Toda (Hiroshima University, Japan)

◆chair : Takashi Toda
・13:00-13:30 Michiko Oyoshi (Harvard University, USA)
Induction of neonatal tolerance through breast milk

・13:30-14:00 Toshiaki Nakano (Kaohsiung Chang Gung Memorial Hospital, Taiwan)
Sunlight and vitamin D for healthy aging

・14:00-14:30 Seiji Kawamoto (Hiroshima University, Japan)　　　　　　　　　　　　　　　　Food factors and disease prevention

　　　　　14:30-14:45 Coffee Break

◆chair : Masaki Mizunuma
・14:45-15:15 Keith Blackwell (Harvard University, USA)
An immunometabolic pathway that modulates lifespan

・15:15-15:45 Takahiro Chihara (Hiroshima University, Japan)
Genetic analysis of olfaction and aging in Drosophila

・15:45-16:15 Hirofumi Aiba (Nagoya University, Japan)
How is fission yeast long-lived? ‘Longevity strategy to learn from yeast’

　　　　　16:15-16:30 Coffee Break

◆chair : Masaru Ueno
・16:30-17:00 Shakil Ahmed (Central Drug Research Institute, India)
Role of Wat1, a TOR complex protein during stress response and its implication in ageing

・17:00-17:30 Jo Murray (University of Sussex, UK)
Replication stress and chromosome instability

Closing Remarks Seiji Kawamoto (Hiroshima University , Japan)

Michiko Oyoshi (Harvard University, USA)

Toshiaki Nakano (Kaohsiung Chang Gung Memorial Hospital, Taiwan)

Seiji Kawamoto (Hiroshima University, Japan)

Keith Blackwell (Harvard University, USA)

Takahiro Chihara (Hiroshima University, Japan)

Hirofumi Aiba (Nagoya University, Japan)

Shakil Ahmed (Central Drug Research Institute, India)

Jo Murray (University of Sussex, UK)

* This lecture is set up as a joint seminar across five graduate schools.

A new paper on which Dr Corinne Pinder (a research scientist in Dr Takashi Toda group) is a co-author, was published. The paper ‘LARP7 family proteins have conserved function in telomerase assembly’ appeared in Nature Communications online.

[NEWS]

A new paper on which Dr Corinne Pinder (a research scientist in Dr Takashi Toda group) is a co-author, was published.

The paper ‘LARP7 family proteins have conserved function in telomerase assembly’ appeared in Nature Communications online.

[SUMMARY]

This work was performed in Dr Kazu Tomita group (University College London, London UK) under collaboration with groups in both London, UK (UCL and Imperial College) and Massachusetts, USA (Salem State University.

The work addresses the important question of telomerase regulation, a crucial enzyme in ageing and cancer, and differences in telomerase biogenesis between species. Specifically, fission yeast Lar7 is a conserved RNA-binding protein that protects telomerase RNA from degradation. Lar7 also stabilises the formation of the mature telomerase complex for its localisation to the telomere for stable genome propagation and healthy ageing.

Dr Corinne Pinder was currently supported by JSPS grant『Fostering international researchers through the collaborative research network focusing on the mechanisms of lifespan regulation』. Dr Kazu Tomita received PhD in Shizuoka University in the laboratory of Dr Masaru Ueno (currently a core member of HiHA).

[PUBLICATIONS]

Collopy LC, Ware TL, Goncalves T, S IK, Yang Q, Amelina H, Pinder C, Alenazi A, Moiseeva V, Pearson SR, Armstrong CA, Tomita K (2018). LARP7 family proteins have conserved function in telomerase assembly. Nat Commun 9, 557.

<https://www.nature.com/articles/s41467-017-02296-4>

Dr Corinne Pinder was supported by a JSPS grant “Program for Advancing Strategic International Networks to Accelerate the Circulation of Talented Researchers”-funded 『Fostering international researchers through the collaborative research network focusing on the mechanisms of lifespan regulation』.

(5th February) A new manuscript from Takashi Toda group (collaboration with Dr Ken-ichi Kimora, Iwate University) was deposited to bioRxiv online.

A new manuscript from Takashi Toda group (collaboration with Dr Ken-ichi Kimora, Iwate University) was deposited to bioRxiv online.

Fission yeast cells overproducing HSET/KIFC1 provides a useful tool for identification and evaluation of human kinesin-14 inhibitors

Masashi Yukawa, Tomoaki Yamauchi, Ken-ichi Kimura and Takashi Toda

doi: https://doi.org/10.1101/257436

A new paper based on international collaboration between Hiroshima University-HiHA (Seiji Kawamoto’s group), Cairo University, Kafrelsheikh University, Suez Canal University, and Minia University was published in the Cytotechnology.