原著論文

• Producing human ceramide-NS by metabolic engineering using yeast Saccharomyces cerevisiae.
  Murakami S, Shimamoto T, Nagano H, Tsuruno M, Okuhara H, Hatanaka H, Tojo H, Kodama Y, Funato K.
  Scientific Reports., 17 Nov 2015, doi: 10.1038/srep16319. [abstract]

• The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation.
  Hori A, Morand A, Ikebe C, Frith D, Snijders AP, Toda T.
  Biochemical and Biophysical Research Communications., 10 Nov 2015, doi: 10.1016/j.bbrc.2015.10.169. [abstract]

• Recombinant Fusion Allergens, Cry j 1 and Cry j 2 from Japanese Cedar Pollen, Conjugated with Polyethylene Glycol Potentiate the Attenuation of Cry j 1-Specific IgE Production in Cry j 1-Sensitized Mice and Japanese Cedar Pollen Allergen-Sensitized Monkeys.
  Fujimura T, Fujinami K, Ishikawa R, Tateno M, Tahara Y, Okumura Y, Ohta H, Miyazaki H, Taniguchi M.
  Int Arch Allergy Immunol., 3 Nov 2015, doi: 10.1159/000441141. [abstract]

• Complementation analysis reveals a potential role of human ARV1 in GPI anchor biosynthesis.
  Ikeda A, Kajiwara K, Iwamoto K, Makino A, Kobayashi T, Mizuta K, Funato K.
  Yeast., 2 Nov 2015, doi: 10.1002/yea.3138. [abstract]

• Casein kinase 1γ acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast.
  Koyano T, Barnouin K, Snijders AP, Kume K, Hirata D, Toda T.
  Genes to Cells., 2 Nov 2015, doi: 10.1111/gtc.12309. [abstract]

• Fission Yeast Exo1 and Rqh1-Dna2 Redundantly Contribute to Resection of Uncapped Telomeres.
  Nanbu T, Nguyễn LC, Habib AG, Hirata N, Ukimori S, Tanaka D, Masuda K, Takahashi K, Yukawa M, Tsuchiya E, Ueno M.
  PLoS One., 14 Oct 2015, doi: 10.1371/journal.pone.0140456. [abstract]

• The yeast chromatin remodeler Rsc1-RSC complex is required for transcriptional activation of autophagy-related genes and inhibition of the TORC1 pathway in response to nitrogen starvation.
  Yu F, Imamura Y, Ueno M, Suzuki SW, Ohsumi Y, Yukawa M, Tsuchiya E.
  Biochem Biophys Res Commun., 4 Sep 2015, doi: 10.1016/j.bbrc.2015.07.114. [abstract]

• Inhibition of the Arg/N-end rule pathway-mediated proteolysis by dipeptide-mimetic molecules.
  Kitamura K.
  Amino acids, 3 Sep 2015, doi:10.​1007/​s00726-015-2083-1. [abstract]

• Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes.
  Ju KS, Gao J, Doroghazi JR, Wang KA, Thibodeaux CJ, Li S, Metzger E, Fudala J, Su J, Zhang JK, Lee J, Cioni JP, Evans BS, Hirota R, Labeda DP, van der Donk WA, Metcalf WW.
  Proc Natl Acad Sci U S A., 31 Aug 2015, doi: 10.1073/pnas.1500873112. [abstract]

• Sphingolipids regulate telomere clustering by affecting transcriptional levels of genes involved in telomere homeostasis.
  Ikeda A, Muneoka T, Murakami S, Hirota A, Yabuki Y, Karashima T, Nakazono K, Tsuruno M, Pichler H, Shirahige K, Kodama Y, Shimamoto T, Mizuta K, Funato K.
  J Cell Sci., 15 Jul 2015, doi: 10.1242/jcs.164160. [abstract]

• Spectrum of allergens for Japanese cedar pollinosis and impact of component-resolved diagnosis  on allergen-specific immunotherapy.
  Fujimura T and Kawamoto S.
  Allergology Int., Published 3 July 2015, doi:10.1016/j.alit.2015.05.008. [abstract]

• The essential function of Rrs1 in ribosome biogenesis is conserved in budding and fission yeasts.
  Wan K, Kawara H, Yamamoto T, Kume K, Yabuki Y, Goshima T, Kitamura K, Ueno M, Kanai M, Hirata D, Funato K, Mizuta K.
  Yeast, 29 Jun 2015, doi: 10.1002/yea.3083. [abstract]

• RSC Chromatin-Remodeling Complex Is Important for Mitochondrial Function in Saccharomyces cerevisiae.
  Imamura Y, Yu F, Nakamura M, Chihara Y, Okane K, Sato M, Kanai M, Hamada R, Ueno M, Yukawa M, Tsuchiya E.
  PLoS One, 18 Jun 2015, doi: 10.1371/journal.pone.0130397. [abstract]

• Long G2 accumulates recombination intermediates and disturbs chromosome segregation at dysfunction telomere in S. pombe.
  Habib AG, Masuda K, Yukawa M, Tsuchiya E, and Ueno M.
  Biochem Biophys Res Commun., Published 18 Jun 2015, doi:10.1016/j.bbrc.2015.06.098. [abstract]

• The Msd1–Wdr8–Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies.
  Yukawa M, Ikebe C and Toda T.
  J Cell Biol, Published 18 May 2015, doi: 10.1083/jcb.201412111. [abstract] [pdf]

• A novel anti-histone H1 monoclonal antibody, SSV monoclonal antibody, improves lung injury and survival in a mouse model of lipopolysaccharide -induced sepsis-like syndrome.
  Kusano T, Chiang KC, Inomata M, Shimada Y, Ohmori N, Goto T, Sato S, Goto S, Nakano T, Kawamoto S, Takaoka Y, Shiraishi N, Noguchi T and Kitano S.
  Biomed Res Int. 2015;2015:491649. doi: 10.1155/2015/491649. [abstract]

• Centriolar satellites- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly.
  Hori A, Peddie CJ, Collinson LM, and Toda T.

  Mol. Biol. Cell, 1 Apl 2015 (online), doi:10.1091/mbc.E14-11-1561. [abstract] [pdf]

• Isolation of a spontaneous cerulenin-resistant sake yeast with both high ethyl caproate-producing ability and normal checkpoint integrity.
  Tamura H, Okada H, Kume K, Koyano T, Goshima T, Nakamura R, Akao T, Shimoi H, Mizunuma M, Ohya Y, Hirata D.
  Biosci Biotechnol Biochem., 19 Mar 2015 (online), doi:10.1080/09168451.2015.1020756. [abstract]

• Casein kinase 1γ ensures monopolar growth polarity under incomplete DNA replication downstream of Cds1 and calcineurin in fission yeast.
  Koyano T, Konishi M, Martin SG, Ohya Y, Hirata D, Toda T, and Kume K.
  Mol Cell Biol., 17 Feb 2015 (online) , doi:10.1128/MCB.01465-14. [abstract]

• Alp7/TACC recruits kinesis-8-PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement.
  Tang NH and Toda T.
  J Cell Sci., 2015 Jan 15, 128(2):354-63. [PubMed]
• Screening for a gene deletion mutant whose temperature sensitivity is suppressed by FK506 in budding yeast and its application for a positive screening for drugs inhibiting calcineurin.
  Kume K, Koyano T, Takara J, Wakabayashi K, Mizunuma M, Miyakawa T, and Hirata D.
  Biosci Biotechnol Biochem., 2015 Jan 23:1-5. [PubMed]
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• Isolation and biosynthesis of an azoxyalkene compound produced by a multiple gene disruptant of Streptomyces rochei.  Hirofumi Kunitake, Takahiro Hiramatsu, Haruyasu Kinashi, Kenji Arakawa. ChemBioChem,16 [15], 2237-2243 (2015). DOI: 10.1002/cbic.201500393
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• The tap-tpg gene pair on the linear plasmid functions to maintain a linear topology of the chromosome in Streptomyces roche.  Yosi Nindita, Zhisheng Cao, Yingjie Yang, Kenji Arakawa, Yuh Shiwa, Hirofumi Yoshikawa, Michihira Tagami, Alexander Lezhava, Haruyasu Kinashi. Mol. Microbiol., 95 [5], 846-858 (2015). DOI: 10.1111/mmi.12904

Review

• 中心小体サテライトとヒトMsd１タンパク質は中心体構築に必須である
  西-堀 晶子、登田　隆
  実験医学（カレントトピックス）, 2015年11月, Vol.33 No.18, 2994-2997

• MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation.
  Tang NH, Toda T.
  Bioessays., 2015 Jan 2., doi: 10.1002/bies.201400175. [PubMed]