{"id":504,"date":"2015-02-12T17:04:56","date_gmt":"2015-02-12T08:04:56","guid":{"rendered":"http:\/\/hiha.hiroshima-u.ac.jp\/?page_id=504"},"modified":"2020-06-01T11:57:24","modified_gmt":"2020-06-01T02:57:24","slug":"results2014-en","status":"publish","type":"page","link":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/results-en\/results2014-en.html","title":{"rendered":"2014"},"content":{"rendered":"<h3>Original papers<\/h3>\r\n<ul>\r\n\t<li>Production of 16.5% v\/v ethanol from seagrass seeds.<br \/>\r\nUchida M, Miyoshi T, Kaneniwa M, Ishihara K, Nakashimada Y, Urano N.<br \/>\r\nJ Biosci Bioeng., 2014 Dec., 118(6):646-50. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24969514\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Dietary restriction involves NAD(+) -dependent mechanisms and a shift toward oxidative metabolism.<br \/>\r\nMoroz N, Carmona JJ, Anderson E, Hart AC, Sinclair DA, Blackwell TK.<br \/>\r\nAging Cell., 2014 Dec., 13(6):1075-85. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25257342\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program.<br \/>\r\nItoh-Nakadai A, Hikota R, Muto A, Kometani K, Watanabe-Matsui M, Sato Y, Kobayashi M, Nakamura A, Miura Y, Yano Y, Tashiro S, Sun J, Ikawa T, Ochiai K, Kurosaki T, Igarashi K.<br \/>\r\nNat Immunol., 2014 Dec., 15(12):1171-80. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25344725\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Dauer-independent insulin\/IGF-1-signalling implicates collagen remodelling in longevity.<br \/>\r\nEwald CY, Landis JN, Abate JP, Murphy CT, Blackwell TK.<br \/>\r\nNature, 2014 Dec 15., doi: 10.1038\/nature14021. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25517099\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>The microbiota is important for IL-17A expression and neutrophil infiltration in lesional skin of Flgft\/ft mice.<br \/>\r\nHoff S, Oyoshi MK, Macpherson A, Geha RS.<br \/>\r\nClin Immunol., 2014 Dec 12., S1521-6616(14)00268-X. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25499749\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>The tap-tpg gene pair on the linear plasmid functions to maintain a linear topology of the chromosome in Streptomyces rochei.<br \/>\r\nNindita Y, Cao Z, Yang Y, Arakawa K, Shiwa Y, Yoshikawa H, Tagami M, Lezhava A, Kinashi H.<br \/>\r\nMol Microbiol., 2014 Dec 11., doi: 10.1111\/mmi.12904. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25495952\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40\/MEK-ERK pathway.<br \/>\r\nMiyamoto J, Mizukure T, Park SB, Kishino S, Kimura I, Hirano K, Bergamo P, Rossi M, Suzuki T, Arita M, Ogawa J, Tanabe S.<br \/>\r\nJ Biol Chem., 2014 Dec 10., jbc.M114.610733. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25505251\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Identification of Pseudomonas fluorescens Chemotaxis Sensory Proteins for Malate, Succinate, and Fumarate, and Their Involvement in Root Colonization.<br \/>\r\nOku S, Komatsu A, Nakashimada Y, Tajima T, Kato J.<br \/>\r\nMicrobes Environ., 2014 Dec 10. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25491753\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Blockage of the early step of lankacidin biosynthesis caused a large production of pentamycin, citreodiol and epi-citreodiol in Streptomyces rochei. <br \/>\r\nCao Z, Yoshida R, Kinashi H, Arakawa K.<br \/>\r\nJ Antibiot., 2014 Dec 3., doi: 10.1038\/ja.2014.160. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25464973\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Binding of WIP to actin is essential for T cell actin cytoskeleton integrity and tissue homing. <br \/>\r\nMassaad MJ, Oyoshi MK, Kane J, Koduru S, Alcaide P, Nakamura F, Ramesh N, Luscinskas FW, Hartwig J, Geha RS.<br \/>\r\nMol Cell Biol., 2014 Dec 1, 34(23):4343-54. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25246631\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Value-added lipid production from brown seaweed biomass by two-stage fermentation using acetic acid bacterium and thraustochytrid.<br \/>\r\nArafiles KH, Iwasaka H, Eramoto Y, Okamura Y, Tajima T, Matsumura Y, Nakashimada Y, Aki T.<br \/>\r\nAppl Microbiol Biotechnol., 2014 Nov, 98(22):9207-16. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25086614\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Clinical outcomes and causes of death in Japanese patients with long-term inferior vena cava filter implants and deep vein thrombosis.<br \/>\r\nIwamoto Y, Okamoto M, Hashimoto M, Fukuda Y, Uchimura Y, Iwamoto A, Matsumoto T, Iwasaki T, Kinoshita H, Ueda H, Kihara Y.<br \/>\r\nJ Cardiol., 2014 Oct, 64(4):308-11. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24679943\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>3,6-Epidioxy-1,10-bisaboladiene inhibits G1 -specific transcription through Swi4\/Swi6 and Mbp1\/Swi6 via the Hog1 stress pathway in yeast.<br \/>\r\nImamura Y, Yukawa M, Ueno M, Kimura K, Tsuchiya E.<br \/>\r\nFEBS J., 2014 Oct, 281(20):4612-21. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25112483\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Evaluation of marine sediments as microbial sources for methane production from brown algae under high salinity.<br \/>\r\nMiura T, Kita A, Okamura Y, Aki T, Matsumura Y, Tajima T, Kato J, Nakashimada Y.<br \/>\r\nBioresour Technol., 2014 Oct, 169:362-6. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25064333\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity. <br \/>\r\nMizunuma, M, Neumann-Haefelin, E, Moroz, N, Li, Y, and Blackwell TK.<br \/>\r\nAging Cell, 2014 Oct, 13:869-878.\u00a0 [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25040785\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Prolonged survival by combined treatment with granulocyte colony-stimulating factor and dipeptidyl peptidase IV inhibitor in a rat small-for-size liver transplantation model.<br \/>\r\nHsu LW, Nakano T, Huang KT, Chen CC, Chen KD, Lai CY, Yang SM, Lin CC, Wang CC, Cheng YF, Chiu KW, Kuo YR, Goto S, Chen CL.<br \/>\r\nHepatol Res., 2014 Sep 2, doi: 10.1111\/hepr.12413. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25179290\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Insights into the diversity of \u03c6RSM phages infecting strains of the phytopathogen Ralstonia solanacearum complex: regulation and evolution.<br \/>\r\nAskora A, Kawasaki T, Fujie M, Yamada T.<br \/>\r\nMol Genet Genomics., 2014 Aug, 289(4):589-98. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24619102\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Targeting Alp7\/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast. <br \/>\r\nTang NH, Okada N, Fong CS, Arai K, Sato M, and Toda T.<br \/>\r\nFEBS Lett., 2014 Aug 25, 588:2814-2821.\u00a0 [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24937146\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Smoking cessation reverses DNA double-strand breaks in human mononuclear cells.<br \/>\r\nIshida M, Ishida T, Tashiro S, Uchida H, Sakai C, Hironobe N, Miura K, Hashimoto Y, Arihiro K, Chayama K, Kihara Y, Yoshizumi M.<br \/>\r\nPLoS One., 2014 Aug 5, 9(8):e103993. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25093845\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Application of a phosphite dehydrogenase gene as a novel dominant selection marker for yeasts. <br \/>\r\nKanda K, Ishida T, Hirota R, Ono S, Motomura K, Ikeda T, Kitamura K, Kuroda A.<br \/>\r\nJ Biotechnol., 2014 Jul 20, 182-183:68-73. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24786825\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Reorganization of damaged chromatin by the exchange of histone variant H2A.Z-2. <br \/>\r\nNishibuchi I, Suzuki H, Kinomura A, Sun J, Liu NA, Horikoshi Y, Shima H, Kusakabe M, Harata M, Fukagawa T, Ikura T, Ishida T, Nagata Y, Tashiro S.<br \/>\r\nInt J Radiat Oncol Biol Phys., 2014 Jul 15, 89(4):736-44. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24969791\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>The filamentous phage XacF1 causes loss of virulence in Xanthomonas axonopodis pv. citri, the causative agent of citrus canker disease. <br \/>\r\nAhmad AA, Askora A, Kawasaki T, Fujie M, Yamada T.<br \/>\r\nFront Microbiol., 2014 Jul 1, 5:321. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25071734\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly. <br \/>\r\nOkada N, Toda T, Yamamoto M, and Sato M.<br \/>\r\nMol Biol Cell., 2014 Jul 1, 25: 1969-1982.\u00a0 [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24790093\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Affinity purification of recombinant proteins using a novel silica-binding peptide as a fusion tag. <br \/>\r\nAbdelhamid MA, Motomura K, Ikeda T, Ishida T, Hirota R, Kuroda A. <br \/>\r\nAppl Microbiol Biotechnol., 2014 Jun, 98(12):5677-84. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24756322\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Late-maturing cooking rice Sensyuraku has excellent properties, equivalent to sake rice, for high-quality sake brewing. <br \/>\r\nAnzawa Y, Satoh K, Satoh Y, Ohno S, Watanabe T, Katsumata K, Kume K, Watanabe K, Mizunuma M, Hirata D.<br \/>\r\nBiosci Biotechnol Biochem., 2014 Jun 26, 78(11):1954-62. \u00a0 [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25351334\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Anti-inflammatory and Intestinal Barrier-protective Activities of Commensal Lactobacilli and Bifidobacteria in Thoroughbreds: Role of Probiotics in Diarrhea Prevention in Neonatal Thoroughbreds. <br \/>\r\nTanabe S, Suzuki T, Wasano Y, Nakajima F, Kawasaki H, Tsuda T, Nagamine N, Tsurumachi T, Sugaya K, Akita H, Takagi M, Takagi K, Inoue Y, Asai Y, Morita H.<br \/>\r\nJ Equine Sci., 2014 Jun 25, 25(2):37-43. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25013357\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Regulation of heme oxygenase 1 expression by miR-27b with stem cell therapy for liver regeneration in rats.<br \/>\r\nChen KD, Hsu LW, Goto S, Huang KT, Nakano T, Weng WT, Lai CY, Kuo YR, Chiu KW, Wang CC, Cheng YF, Lin CC, Ma YY, Chen CL.<br \/>\r\nTransplant Proc., 2014 May, 46(4):1198-200. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24815159\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma.<br \/>\r\nChen KD, Wang CC, Tsai MC, Wu CH, Yang HJ, Chen LY, Nakano T, Goto S, Huang KT, Hu TH, Chen CL, Lin CC.<br \/>\r\nCell Death Dis., 2014 May 22, 5:e1244. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24853422\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>The ClpS-like N-domain is essential for the functioning of Ubr11, an N-recognin in Schizosaccharomyces pombe.<br \/>\r\nKitamura K.<br \/>\r\nSplingerPlus, 2014 May 20, 3:257. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26034658\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Genetic and metabolomic dissection of the ergothioneine and selenoneine biosynthetic pathway in the fission yeast, S. pombe, and construction of an overproduction system.<br \/>\r\nPluskal T, Ueno M, Yanagida M.<br \/>\r\nPLoS One., 2014 May 14, 9(5):e97774. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24828577\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Nap1 stimulates homologous recombination by RAD51 and RAD54 in higher-ordered chromatin containing histone H1.<br \/>\r\nMachida S, Takaku M, Ikura M, Sun J, Suzuki H, Kobayashi W, Kinomura A, Osakabe A, Tachiwana H, Horikoshi Y, Fukuto A, Matsuda R, Ura K, Tashiro S, Ikura T, Kurumizaka H.<br \/>\r\nSci Rep., 2014 May 6, 4:4863. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24798879\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Elevation of C-reactive protein level and its correlation with psychiatric comorbidities in recipients after liver transplantation.<br \/>\r\nChen CC, Hsu LW, Nakano T, Goto S, Chen CL.<br \/>\r\nTransplant Proc., 2014 Apr, 46(3):894-6. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24767374\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>A new subfamily of polyphosphate kinase 2 (class III PPK2) catalyzes both nucleoside monophosphate phosphorylation and nucleoside diphosphate phosphorylation.<br \/>\r\nMotomura K, Hirota R, Okada M, Ikeda T, Ishida T, Kuroda A.<br \/>\r\nAppl Environ Microbiol., 2014 Apr, 80(8):2602-8. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24532069\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Enhancement of (R)-1,3-butanediol production by engineered Escherichia coli using a bioreactor system with strict regulation of overall oxygen transfer coefficient and pH.<br \/>\r\nKataoka N, Vangnai AS, Ueda H, Tajima T, Nakashimada Y, Kato J.<br \/>\r\nBiosci Biotechnol Biochem., 2014 Apr 23, 78(4):695-700. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25036969\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.<br \/>\r\nMiyagawa K, Low RS, Santosa V, Tsuji H, Moser BA, Fujisawa S, Harland JL, Raguimova ON, Go A, Ueno M, Matsuyama A, Yoshida M, Nakamura TM, Tanaka K.<br \/>\r\nProc Natl Acad Sci U S A., 2014 Apr 22, 111(16):5950-5. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24711392\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Genetic and biochemical analysis of the antibiotic biosynthetic gene clusters on the Streptomyces linear plasmid.<br \/>\r\nArakawa K.<br \/>\r\nBiosci Biotechnol Biochem., 2014 Apr 16, 78(2):183-9. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25036669\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Administered chrysanthemum flower oil attenuates hyperuricemia: mechanism of action as revealed by DNA microarray analysis.<br \/>\r\nHonda S, Kawamoto S, Tanaka H, Kishida H, Kitagawa M, Nakai Y, Abe K, Hirata D.<br \/>\r\nBiosci Biotechnol Biochem., 2014 Apr 16, 78(4):655-61. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25036964\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice. <br \/>\r\nTakaoka Y, Goto S, Nakano T, Tseng HP, Yang SM, Kawamoto S, Ono K, Chen CL.<br \/>\r\nSci Rep., 2014 Apr 6, 4:5204. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24902773\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Rad51-dependent aberrant chromosome structures at telomeres and ribosomal DNA activate the spindle assembly checkpoint. <br \/>\r\nNakano A, Masuda K, Hiromoto T, Takahashi K, Matsumoto Y, Habib AG, Darwich AG, Yukawa M, Tsuchiya E, and Ueno M.<br \/>\r\nMol Cell Biol., 2014 Apr, 34:1389-1397.\u00a0 [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24469396\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Assessment of reasons for referral and activities of hospital palliative care teams using a standard format: a multicenter 1000 case description.<br \/>\r\nSasahara T, Watakabe A, Aruga E, Fujimoto K, Higashi K, Hisahara K, Hori N, Ikenaga M, Izawa T, Kanai Y, Kinoshita H, Kobayakawa M, Kobayashi K, Kohara H, Namba M, Nozaki-Taguchi N, Osaka I, Saito M, Sekine R, Shinjo T, Suga A, Tokuno Y, Yamamoto R, Yomiya K, Morita T.<br \/>\r\nJ Pain Symptom Manage., 2014 Mar, 47(3):579-587.e6. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23972575\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Degradation of chloroanilines by toluene dioxygenase from Pseudomonas putida T57.<br \/>\r\nNitisakulkan T, Oku S, Kudo D, Nakashimada Y, Tajima T, Vangnai AS, Kato J.<br \/>\r\nJ Biosci Bioeng., 2014 Mar, 117(3):292-7. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24064298\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>GLTSCR2\/PICT1 links mitochondrial stress and Myc signaling.<br \/>\r\nYoon JC, Ling AJ, Isik M, Lee DY, Steinbaugh MJ, Sack LM, Boduch AN, Blackwell TK, Sinclair DA, Elledge SJ.<br \/>\r\nProc Natl Acad Sci U S A., 2014 Mar 11, 111(10):3781-6. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24556985\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>IL-10 suppresses IL-17-mediated dermal inflammation and reduces the systemic burden of Vaccinia virus in a mouse model of eczema vaccinatum.<br \/>\r\nDarling AR, Freyschmidt EJ, Burton OT, Koleoglou KJ, Oyoshi MK, Oettgen HC.<br \/>\r\nClin Immunol., 2014 Feb, 150(2):153-60. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24412909\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Regulation of polyunsaturated fatty acid biosynthesis by seaweed fucoxanthin and its metabolite in cultured hepatocytes.<br \/>\r\nAki T, Yamamoto M, Takahashi T, Tomita K, Toyoura R, Iwashita K, Kawamoto S, Hosokawa M, Miyashita K, Ono K.<br \/>\r\nLipids., 2014 Feb, 49(2):133-41. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24174374\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>The oxidative stress responsive transcription factor Pap1 confers DNA damage resistance on checkpoint-deficient fission yeast cells.<br \/>\r\nBelfield C, Queenan C, Rao H, Kitamura K, Walworth NC.<br \/>\r\nPLoS One., 2014 Feb 25, 9(2):e89936. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24587136\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Msd1\/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation.<br \/>\r\nHori A, Ikebe C, Tada M, and Toda T.<br \/>\r\nEMBO Rep., 2014 Feb, 15:175-184.\u00a0 [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24397932\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Characterization of bacteriophages Cp1 and Cp2, the strain-typing agents for Xanthomonas axonopodis pv. citri. <br \/>\r\nAhmad AA, Ogawa M, Kawasaki T, Fujie M, Yamada T.<br \/>\r\nAppl Environ Microbiol., 2014 Jan, 80(1):77-85. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24123743\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast. <br \/>\r\nKajiwara K, Ikeda A, Aguilera-Romero A, Castillon GA, Kagiwada S, Hanada K, Riezman H, Muniz M, and Funato K. <br \/>\r\nJ Cell Sci., 2014 Jan 15, 15:376-387.\u00a0 [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24213531\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<h3>Review<\/h3>\r\n<ul>\r\n\t<li>Food allergy: Insights into etiology, prevention, and treatment provided by murine models. <br \/>\r\nOyoshi MK, Oettgen HC, Chatila TA, Geha RS, Bryce PJ. <br \/>\r\nJ Allergy Clin Immunol., 2014 Feb, 133(2):309-17. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24636470\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">PubMed<\/span><\/a>]<\/li>\r\n\t<li>Role of DNA Damage in Cardiovascular Disease. <br \/>\r\nIshida T, Ishida M, Tashiro S, Yoshizumi M, Kihara Y. <br \/>\r\nCirculation Journal, 2014 Jan, Vol. 78 (2014) No. 1 42-50. [<a href=\"https:\/\/www.jstage.jst.go.jp\/article\/circj\/78\/1\/78_CJ-13-1194\/_article\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">Abstract<\/span><\/a>]<\/li>\r\n\t<li>\u00a0<\/li>\r\n\t<li>Blockage of the early step of lankacidin biosynthesis caused a large production of pentamycin, citreodiol, and <em>epi<\/em>-citreodiol in <em>Streptomyces<\/em> <em>rochei. \u00a0Zhisheng Cao, Ryuhei Yoshida, Haruyasu Kinashi, <\/em>Kenji Arakawa.\u00a0<strong>J. Antibiot.<\/strong>, <em>68<\/em> [5], 328-333 (2015). DOI: 10.1038\/ja.2014.160<\/li>\r\n<\/ul>","protected":false},"excerpt":{"rendered":"Original papers Production of 16.5% v\/v ethanol from seagrass seeds. Uchida M, Miyoshi T, Kaneniwa M, Ishihara K, Nakashimada Y, Urano N. J Biosci Bioeng., 2014 Dec., 118(6):646-50. [PubMed] Dietary restriction involves NAD(+) -dependent mechanisms and a shift toward oxidative metabolism. Moroz N, Carmona JJ, Anderson E, Hart AC, Sinclair DA, Blackwell TK. Aging Cell., 2014 Dec., 13(6):1075-85. [PubMed] The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program. Itoh-Nakadai A, Hikota R, Muto A, Kometani K, Watanabe-Matsui M, Sato Y, Kobayashi M, Nakamura A, Miura Y, Yano Y, Tashiro S, Sun J, Ikawa T, Ochiai K, Kurosaki T, Igarashi K. Nat Immunol., 2014 Dec., [&hellip;]","protected":false},"author":1,"featured_media":0,"parent":502,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/504"}],"collection":[{"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/comments?post=504"}],"version-history":[{"count":0,"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/504\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/502"}],"wp:attachment":[{"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/media?parent=504"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}