{"id":1605,"date":"2017-04-27T19:31:54","date_gmt":"2017-04-27T10:31:54","guid":{"rendered":"http:\/\/hiha.hiroshima-u.ac.jp\/?page_id=1605"},"modified":"2018-01-30T23:03:38","modified_gmt":"2018-01-30T14:03:38","slug":"results-en2017","status":"publish","type":"page","link":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/results-en\/results-en2017.html","title":{"rendered":"2017"},"content":{"rendered":"<h3>Original papers<\/h3>\r\n<ul>\r\n\t<li>Design, Synthesis and Cytotoxicity Evaluation of New 3, 5-Disubstituted-2-Thioxoimidazolidinones.<br \/>\r\n Abdellatif K, Elbadawi MM, Elsaady MT, El-Hafeez AAA, Fujimura T, Kawamoto S, Khodair AI.<br \/>\r\n Anticancer Agents Med Chem. 2017 Nov 29. doi: 10.2174\/1871520618666171129213838. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29189182\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Fission yeast strains with circular chromosomes require the 9-1-1 checkpoint complex for the viability in response to the anti-cancer drug 5-fluorodeoxyuridine.<br \/>\r\n Shamim HM, Minami Y, Tanaka D, Ukimori S, Murray JM, Ueno M.<br \/>\r\n PLoS One. 2017 Nov 9;12(11):e0187775. doi: 10.1371\/journal.pone.0187775. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5679574\/\" target=\"_blank\" rel=\"noopener\">abstract<\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Two spatially distinct Kinesin-14 Pkl1 and Klp2 generate collaborative inward forces against Kinesin-5 Cut7 in S. pombe<br \/>\r\n Yukawa M, Yamada Y, Yamauchi T, Toda T<br \/>\r\n J Cell Sci 2017 : doi: 10.1242\/jcs.210740 [<a href=\"http:\/\/jcs.biologists.org\/content\/early\/2017\/11\/22\/jcs.210740\" target=\"_blank\" rel=\"noopener\">abstract<\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Generation and characterisation of temperature sensitive mutants of genes encoding the fission yeast spindle pole body.<br \/>\r\n Tang NH\u200b, Fong CS\u200b, Masuda H, Jourdain I, Yukawa M, Toda T\u200b<br \/>\r\n PeerJ Preprints 5, e3377v1, DOI: 10.7287\/peerj.preprints.3377v1 [<a href=\"https:\/\/peerj.com\/preprints\/3377\/\" target=\"_blank\" rel=\"noopener\">abstract<\/a>]<br \/>\r\n Methods in Molecular Biology, accepted.<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>A microtubule polymerase cooperates with the Kinesin-6 motor and a microtubule crosslinker to promote bipolar spindle assembly in the absence of Kinesin-5 and Kinesin-14 in fission yeast.<br \/>\r\n Yukawa M, Kawakami T, Okazaki M, Kume K, Tang NH, Toda T.<br \/>\r\n Mol Biol Cell. 2017 Oct 11. pii: mbc.E17-08-0497. doi: 10.1091\/mbc.E17-08-0497. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29021344\" target=\"_blank\" rel=\"noopener\">abstract<\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Prominent IgE-binding and cytokine-inducing capacities of a newly cloned N-terminal region of Der f 14, an apolipophorin-like house dust mite allergen.<br \/>\r\n ElRamlawy KG, Fujimura T, Aki T, Okada A, Suzuki T, Abe T, Hayashi T, Epton MJ, Thomas WR, Rafeet IH, Al-Azhary DB, Ono K, Kawamoto S.<br \/>\r\n J Biochem. 2017 Sep 11. doi: 10.1093\/jb\/mvx060. [<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28992042\" target=\"_blank\" rel=\"noopener\">abstract<\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Time-course microarrays reveal early activation of the immune transcriptome in a choline-deficient mouse model of liver injury.<br \/>\r\n Mitsumoto K, Watanabe R, Nakao K, Yonenaka H, Hashimoto T, Kato N, Kumrungsee T, Yanaka N.<br \/>\r\n Life Sci. 2017 Sep 1;184:103-111. doi: 10.1016\/j.lfs.2017.07.009. Epub 2017 Jul 12.\u00a0[<a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0024320517303296?via%3Dihub\" target=\"_blank\" rel=\"noopener\">abstract<\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Plasma Cluster Ions Reduce the IgE-Binding Capacity of House Dust Mite Allergens under a Simulated Indoor Environmental Condition.<br \/>\r\n Okano H, Fujimura T, Fukuoka N, Hayashi T, Nishikawa K, Ono K, Kawamoto S.<br \/>\r\n Int Arch Allergy Immunol. 2017 Aug 29;173(4):199-203. doi: 10.1159\/000477724.\u00a0[<a href=\"http:\/\/www.karger.com\/DOI\/10.1159\/000477724\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Synergistic tumor suppression by a Perilla frutescens-derived methoxyflavanone and anti-cancer tyrosine kinase inhibitors in A549 human lung adenocarcinoma.<br \/>\r\n Abd El-Hafeez AA, Fujimura T, Kamei R, Hirakawa N, Baba K, Ono K, Kawamoto S<br \/>\r\n Cytotechnology. 2017 Jul 29. doi: 10.1007\/s10616-017-0124-1 [<a href=\"https:\/\/link.springer.com\/article\/10.1007\/s10616-017-0124-1\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>A novel moonlight function of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) for immunomodulation.<br \/>\r\n Nakano T, Goto S, Takaoka Y, Tseng HP, Fujimura T, Kawamoto S, Ono K, Chen CL.<br \/>\r\n Biofactors. 2017 Jul 28. doi: 10.1002\/biof.1379.\u00a0[<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/biof.1379\/abstract;jsessionid=2425807DF798879C672EF5519CBA5694.f04t03\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Identification of three signaling molecules required for calcineurin-dependent monopolar growth induced by the DNA replication checkpoint in fission yeast.<br \/>\r\n Kume K, Hashimoto T, Suzuki M, Mizunuma M, Toda T, Hirata D.<br \/>\r\n Biochem Biophys Res Commun. 2017 Jul 24. pii: S0006-291X(17)31487-0. doi: 10.1016\/j.bbrc.2017.07.129.\u00a0[<a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X17314870?via%3Dihub\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>A methoxyflavanone derivative from the Asian medicinal herb (Perilla frutescens) induces p53-mediated G2\/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma.<br \/>\r\n Abd El-Hafeez AA, Fujimura T, Kamei R, Hirakawa N, Baba K, Ono K, Kawamoto S<br \/>\r\n Cytotechnology. 2017 Jul 14. doi: 10.1007\/s10616-017-0116-1. [<a href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs10616-017-0116-1\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>A systematic genomic screen implicates nucleocytoplasmic transport and membrane growth in nuclear size control.<br \/>\r\n Kume K, Cantwell H, Neumann FR, Jones AW, Snijders AP, Nurse P.<br \/>\r\n PLoS Genet. 2017 May 18;13(5):e1006767. doi: 10.1371\/journal.pgen.1006767. eCollection 2017 May.\u00a0 [<a href=\"http:\/\/journals.plos.org\/plosgenetics\/article?id=10.1371\/journal.pgen.1006767\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Purification and characterisation of the fission yeast Ndc80 complex.<br \/>\r\n Matsuo Y, Maurer SP, Surrey T, Toda T.<br \/>\r\n Protein Expr Purif. 2017 May 11;135:61-69. doi: 10.1016\/j.pep.2017.05.002.\u00a0 [<a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S104659281730075X\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Der f 35: an MD-2-like house dust mite allergen that cross-reacts with Der f 2 and Pso o 2.<br \/>\r\n Fujimura T, Aki T, Isobe T, Matsuoka A, Hayashi T, Ono K, Kawamoto S.<br \/>\r\n Allergy. 2017 Apr 25. doi: 10.1111\/all.13192.\u00a0 [<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/all.13192\/abstract;jsessionid=8D44AEA977A49265560A16E106181CA5.f04t02\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>A genetic method to enhance the accumulation of S-adenosylmethionine in yeast.<br \/>\r\n Kanai M, Mizunuma M, Fujii T, Iefuji H.<br \/>\r\n Appl Microbiol Biotechnol. 2017 Feb;101(4):1351-1357. doi: 10.1007\/s00253-017-8098-7. Epub 2017 Jan 11. Review.\u00a0[<a href=\"http:\/\/link.springer.com\/article\/10.1007%2Fs00253-017-8098-7\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<ul>\r\n\t<li>Arp2\/3 complex and Mps3 are required for regulation of ribosome biosynthesis in the secretory stress response.<br \/>\r\n Yabuki Y, Katayama M, Kodama Y, Sakamoto A, Yatsuhashi A, Funato K, Mizuta K.<br \/>\r\n Yeast. 2017 Apr;34(4):155-163. doi: 10.1002\/yea.3221. Epub 2017 Jan 12.\u00a0[<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/yea.3221\/abstract\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #0000ff;\">abstract<\/span><\/a>]<\/li>\r\n<\/ul>\r\n<p>&nbsp;<\/p>\r\n<h3>Review<\/h3>","protected":false},"excerpt":{"rendered":"Original papers Design, Synthesis and Cytotoxicity Evaluation of New 3, 5-Disubstituted-2-Thioxoimidazolidinones. Abdellatif K, Elbadawi MM, Elsaady MT, El-Hafeez AAA, Fujimura T, Kawamoto S, Khodair AI. Anticancer Agents Med Chem. 2017 Nov 29. doi: 10.2174\/1871520618666171129213838. [abstract] Fission yeast strains with circular chromosomes require the 9-1-1 checkpoint complex for the viability in response to the anti-cancer drug 5-fluorodeoxyuridine. Shamim HM, Minami Y, Tanaka D, Ukimori S, Murray JM, Ueno M. PLoS One. 2017 Nov 9;12(11):e0187775. doi: 10.1371\/journal.pone.0187775. [abstract] Two spatially distinct Kinesin-14 Pkl1 and Klp2 generate collaborative inward forces against Kinesin-5 Cut7 in S. pombe Yukawa M, Yamada Y, Yamauchi T, Toda T J Cell Sci 2017 : doi: 10.1242\/jcs.210740 [abstract] Generation [&hellip;]","protected":false},"author":5,"featured_media":0,"parent":502,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/1605"}],"collection":[{"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/comments?post=1605"}],"version-history":[{"count":0,"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/1605\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/pages\/502"}],"wp:attachment":[{"href":"https:\/\/hiha.hiroshima-u.ac.jp\/en\/wp-json\/wp\/v2\/media?parent=1605"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}