Dr Corinne Pinder was supported by a JSPS grant “Program for Advancing Strategic International Networks to Accelerate the Circulation of Talented Researchers”-funded 『Fostering international researchers through the collaborative research network focusing on the mechanisms of lifespan regulation』.
A new paper on which Dr Corinne Pinder (a research scientist in Dr Takashi Toda group) is a co-author, was published.
The paper ‘LARP7 family proteins have conserved function in telomerase assembly’ appeared in Nature Communications online.
This work was performed in Dr Kazu Tomita group (University College London, London UK) under collaboration with groups in both London, UK (UCL and Imperial College) and Massachusetts, USA (Salem State University.
The work addresses the important question of telomerase regulation, a crucial enzyme in ageing and cancer, and differences in telomerase biogenesis between species. Specifically, fission yeast Lar7 is a conserved RNA-binding protein that protects telomerase RNA from degradation. Lar7 also stabilises the formation of the mature telomerase complex for its localisation to the telomere for stable genome propagation and healthy ageing.
Dr Corinne Pinder was currently supported by JSPS grant『Fostering international researchers through the collaborative research network focusing on the mechanisms of lifespan regulation』. Dr Kazu Tomita received PhD in Shizuoka University in the laboratory of Dr Masaru Ueno (currently a core member of HiHA).
Collopy LC, Ware TL, Goncalves T, S IK, Yang Q, Amelina H, Pinder C, Alenazi A, Moiseeva V, Pearson SR, Armstrong CA, Tomita K (2018). LARP7 family proteins have conserved function in telomerase assembly. Nat Commun 9, 557.